What is biobanking?
What is biobanking and how can it help you?
The short answer is: A biobank is a repository of appropriately preserved biological samples forthe purpose of future scientific research.
However, biobanking has a far more complex explanation in the scientific research arena.
Time magazine named Biobanking one of the "10 Most Innovative Ideas" in 2009.
"Changing the World Today" They highlighted how biobanks can elevate the world.
Potential information scientists could derive from biological samples.
It will be used for future research.
Biobanks are now an integral part of scientific advancement in the era when science is moving at a rapid pace.
There are many scientific breakthroughs and emerging methods. We now know that
Biobanking does more than just store biological samples.
Preservation of biological data by appropriate logistical management and legislation
Biobanks act as long-term, large storage libraries of biological data that can be accessed on a large scale.
accessed in order to answer scientific questions on command.
What are the requirements for biobanking success?
The Mayo Clinic is located in Minnesota and was an early adopter for the biobank concept.
He currently manages one among the largest biobanks of patient samples in the United States.
Recently, their researchers published an informative review that defined the requirements for
the successful operations involved in biobanking. These considerations are discussed in this article
Eleanor Roosevelt wisely observed: "Those failing to plan, plan not to fail."
Biobank collection is not complete without a plan.
The plan must be clearly defined and include specific goals and objectives.
You can achieve this by storing the samples. It will also need specific protocols concerning sample handling.
Processing and collection. Storage requirements regarding storage size and conditions.
need to be defined, as well as the long-term monitoring requirements of the specific biobank.
2. Standard Operating Procedures created
Standard Operating Procedures (SOP) are fundamental components of high-quality scientific outputs.
To ensure consistent, repeatable and reliable results in science, there are procedures (SOPs).
The technicians should control sample variability before samples can be sent to the biobank
Researchers responsible for the collection and processing of samples. Once the samples are received at the
biobank, which offers a variety of methods to monitor environmental conditions.
You can limit variability during preservation phase.
These procedures also include handling of specimens.
processing and receiving methodologies. Implementation of the appropriate
record management system, equipment maintenance, monitoring and facility security will all rest
These procedures will be set up by the biobank.
3. Biobank staff training
Staff must have the ability to identify and report on any potential problems with samples that are being used for biobanking.
An in-depth understanding of internal procedures is necessary.
Competent to perform their duties.
Particularly important for biobanks that handle specimens is staff competency and training
all samples were taken from different locations. Further, the Mayo Clinic review authors.
It is a good idea to identify a super-trainer - someone who works as part of your permanent staff.
Training new staff is the responsibility of this department. to ensure a standardised training approach to deliver
Staff turnover makes it impossible to maintain consistency over a long period.
4. Laboratory Information Management Systems
After samples have been stored in the biobank, it is difficult to maintain the integrity of the sample.
Sample integrity further relies on the ongoing, day-to-day activities of the biobank. These activities are heavily dependent on a reliable Laboratory Information Management System, (LIMS), for sample tracking and traceability.
A suitable LIMS software suite allows for the management and tracking laboratory samples and associated data. It is important to document all details about each sample's type, source, collection, collection method, transportation, processing and preservation (if any).
Depending on the unique requirements of the specific biobank, LIMS can be integrated with specialised instrumentation and workflows to further eliminate the potential for human error that could compromise the integrity of the samples in the biorepository.
5. Processing after collection
In order to ensure long-term storage, depending on the nature of biological samples, processing after collection may be required.
The post-collection process should be clearly defined in the SOPs. This should be included within the LIMS in order to preserve the integrity of each specimen.
6. Disaster preparedness
Samples stored in a biobank are often scientifically valuable and irreplaceable.
Biobanks must be prepared for any potential natural disasters that could threaten the integrity and preservation of samples. Depending on the area and environmental conditions of the biobank, some potential threats could include fires, floods, natural disasters and security breaches.
A biobank should not only have an early detection system in place but it is also recommended that a designated crisis management team be assigned to prepare risk assessments and a tailor-made contingency plan, should disaster strike.
Biobanking in South Africa: unique challenges and prospects
With a current population of approximately 60 million people, South Africa has one of the highest rates of communicable diseases including HIV, Tuberculosis, and a growing list of metabolic disease syndromes.
This high incidence of diseases requires specialized research and development in order for developing countries with logistical and resource limitations to be able to benefit from it.
The limitations of South Africa’s energy resources is one of the biggest threats to productivity. Rolling, scheduled power cuts have plagued South Africa since 2007, due to a combination between aging infrastructure, an increase in consumer demand, and limited coal stocks. While the future of SA's energy is dependent on capacity-building and renewable energy, unavoidable power shortfalls are still a constant threat.
Since effectively maintaining specified temperatures in sample storage is crucial, special considerations must be given to biorepositories in SA regarding their energy supply. A reputable SA-based biorepository will require backup generators and stable energy storage devices to ensure sustained operations.
Consider biobanking to store your samples.
Biobanking can seem like something that is only available to large research institutions and academic institutions.